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Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis.
Dönig, Judith; Mende, Hannah; Davila Gallesio, Jimena; Wagner, Kristina; Hotz, Paul; Schunck, Kathrin; Piller, Tanja; Hölper, Soraya; Uhan, Sara; Kaulich, Manuel; Wirth, Matthias; Keller, Ulrich; Tascher, Georg; Bohnsack, Katherine E; Müller, Stefan.
Afiliação
  • Dönig J; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.
  • Mende H; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.
  • Davila Gallesio J; Department of Molecular Biology, University Medical Centre Göttingen, Humboldtallee 23, 37073, Göttingen, Germany.
  • Wagner K; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.
  • Hotz P; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.
  • Schunck K; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.
  • Piller T; PharmBioTec gGmbH, Schiffweiler, Germany.
  • Hölper S; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.
  • Uhan S; Sanofi AG, Frankfurt, Germany.
  • Kaulich M; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.
  • Wirth M; Sanofi AG, Frankfurt, Germany.
  • Keller U; Department of Hematology, Oncology and Cancer Immunology (Campus Benjamin Franklin), Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Hindenburgdamm 30, 12203, Berlin, Germany.
  • Tascher G; German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Bohnsack KE; Max Delbrück Center, Robert-Rössle-Str. 10, 13125, Berlin, Germany.
  • Müller S; Institute of Biochemistry II, Goethe University Frankfurt, Medical Faculty, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.
Nat Commun ; 14(1): 8121, 2023 Dec 08.
Article em En | MEDLINE | ID: mdl-38065954

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ribossomos / Cisteína Endopeptidases / Proteína Supressora de Tumor p53 Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ribossomos / Cisteína Endopeptidases / Proteína Supressora de Tumor p53 Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article