Bronchopulmonary dysplasia: temporal trend from 2010 to 2019 in the Brazilian Network on Neonatal Research.
Arch Dis Child Fetal Neonatal Ed
; 109(3): 328-335, 2024 Apr 18.
Article
em En
| MEDLINE
| ID: mdl-38071522
ABSTRACT
OBJECTIVE:
To evaluate the temporal trend of bronchopulmonary dysplasia (BPD) in preterm infants who survived to at least 36 weeks' post-menstrual age (PMA) and BPD or death at 36 weeks' PMA, and to analyse variables associated with both outcomes.DESIGN:
Retrospective cohort with data retrieved from an ongoing national registry.SETTING:
19 Brazilian university public hospitals. PATIENTS Infants born between 2010 and 2019 with 23-31 weeks and birth weight 400-1499 g. MAIN OUTCOMEMEASURES:
Temporal trend was evaluated by Prais-Winsten model and variables associated with BPD in survivors or BPD or death were analysed by logistic regression.RESULTS:
Of the 11 128 included infants, BPD in survivors occurred in 22%, being constant over time (annual per cent change (APC) -0.80%; 95% CI -2.59%; 1.03%) and BPD or death in 45%, decreasing over time (APC -1.05%; 95% CI -1.67%; -0.43%). Being male, small for gestational age, presenting with respiratory distress syndrome, air leaks, needing longer duration of mechanical ventilation, presenting with treated patent ductus arteriosus and late-onset sepsis were associated with an increase in the chance of BPD. For the outcome BPD or death, maternal bleeding, multiple gestation, 5-minute Apgar <7, late-onset sepsis, necrotising enterocolitis and intraventricular haemorrhage were added to the variables reported above as increasing the chance of the outcome.CONCLUSION:
The frequency of BPD in survivors was constant and BPD or death decreased by 1.05% at each study year. These results show some improvement in perinatal care in Brazilian units which resulted in a reduction of BPD or death, but further improvements are still needed to reduce BPD in survivors.
Texto completo:
1
Base de dados:
MEDLINE
País como assunto:
America do sul
/
Brasil
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article