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Impact of COVID-19 lockdown on glycemic levels during pregnancy: A retrospective analysis.
Di Zazzo, Erika; Davinelli, Sergio; Panichella, Serena; Scapagnini, Giovanni; Intrieri, Mariano; Garofalo, Silvio.
Afiliação
  • Di Zazzo E; UOC Laboratorio Analisi, Ospedale "A. Cardarelli", 86100 Campobasso, Italy.
  • Davinelli S; Department of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.
  • Panichella S; Department of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.
  • Scapagnini G; Department of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.
  • Intrieri M; Department of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.
  • Garofalo S; Department of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.
Open Med (Wars) ; 18(1): 20230862, 2023.
Article em En | MEDLINE | ID: mdl-38075035
Studies on the COVID-19 pandemic effects on gestational diabetes mellitus (GDM) remain limited and controversial. This study aimed to investigate the impact of the COVID-19 lockdown on the glycemic balance of pregnant women and GDM risk. To this aim, a single-center retrospective cohort analysis assessing glucose homeostasis using the oral glucose tolerance test in 862 pregnant women before (from March 9, 2019 to March 8, 2020 - Group 1), during (from March 9, 2020 to March 8, 2021 - Group 2), and after (from March 9, 2021 to March 8, 2022 - Group 3) the COVID-19 lockdown in Molise, a region of central Italy, was conducted. We observed that the blood glucose concentration of pregnant women was significantly lower during the COVID-19 lockdown than during the previous and following years at all time points evaluated (time 0, 60', and 120'). Specifically, at time 0, it was 82.14 mg/dl for group 2 vs 85.94 for group 1 (p = 0.0001) and 85.87 for group 3 (p = 0.001). Similarly, at 60', it was 121.38 mg/dl for group 2 vs 129.30 mg/dl for group 1 (p = 0.0029) and 131.68 mg/dl for group 3 (p = 0.0006). Moreover, at 120', it was 104.20 mg/dl for group 2 vs 111.51 mg/dl (p = 0.0004) for group 1, and 116.06 mg/dl for group 3 (p = 0.0001). In contrast with previous findings, the COVID-19 lockdown was associated with an improved glycemic balance. Further studies are needed to better clarify the influence of lockdown restrictions on glucose metabolism and, consequently, on GDM risk.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article