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Understanding the impact of mannitol on physical stability and aerosolization of spray-dried protein powders for inhalation.
Arte, Kinnari S; Tower, Cole W; Mutukuri, Tarun T; Chen, Yuan; Patel, Sajal M; Munson, Eric J; Tony Zhou, Qi.
Afiliação
  • Arte KS; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, IN 47907, USA.
  • Tower CW; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, IN 47907, USA.
  • Mutukuri TT; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, IN 47907, USA; Injectable Drug Product Development, Alexion - AstraZeneca Rare Disease Unit, New Haven, CT 06510, USA(1).
  • Chen Y; Dosage Form Design & Development, Biopharmaceutical Development, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD 20878, USA; Global Product Quality, Global Quality Operations, AstraZeneca, Gaithersburg, MD 20787, USA(1).
  • Patel SM; Dosage Form Design & Development, Biopharmaceutical Development, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD 20878, USA.
  • Munson EJ; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, IN 47907, USA.
  • Tony Zhou Q; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, IN 47907, USA. Electronic address: tonyzhou@purdue.edu.
Int J Pharm ; 650: 123698, 2024 Jan 25.
Article em En | MEDLINE | ID: mdl-38081559

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Excipientes / Manitol Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Excipientes / Manitol Idioma: En Ano de publicação: 2024 Tipo de documento: Article