Shape-Tension Coupling Produces Nematic Order in an Epithelium Vertex Model.
Phys Rev Lett
; 131(22): 228301, 2023 Dec 01.
Article
em En
| MEDLINE
| ID: mdl-38101347
ABSTRACT
We study the vertex model for epithelial tissue mechanics extended to include coupling between the cell shapes and tensions in cell-cell junctions. This coupling represents an active force which drives the system out of equilibrium and leads to the formation of nematic order interspersed with prominent, long-lived +1 defects. The defects in the nematic ordering are coupled to the shape of the cell tiling, affecting cell areas and coordinations. This intricate interplay between cell shape, size, and coordination provides a possible mechanism by which tissues could spontaneously develop long-range polarity through local mechanical forces without resorting to long-range chemical patterning.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fenômenos Mecânicos
/
Junções Intercelulares
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article