The 'Pants-Sign': A Predictor for Falling in People with Parkinson's Disease?
J Parkinsons Dis
; 13(8): 1321-1327, 2023.
Article
em En
| MEDLINE
| ID: mdl-38108362
ABSTRACT
BACKGROUND:
A history of falls is the most established predictor of future falls in people with Parkinson's disease (PD). However, predicting a first fall remains challenging.OBJECTIVE:
To assess whether experiencing difficulties putting on pants while standing is a viable predictor of future falling, and specifically a first fall, in persons with PD. We define this 'Pants-sign' as people who resort to putting on their pants only while seated.METHODS:
264 persons with PD were included. Information on the Pants-sign, history of falls, disease severity (MDS-UPDRS part III), freezing of gait (N-FOGQâ>â0), cognitive function (MoCA), self-reported disability (Schwab & England scale), health-related quality of life (SF-12), Timed-Up-and-Go, and one-legged stance were determined at baseline and after one-year follow-up. The association between the Pants-sign and future falling was examined by univariate logistic regression analysis. A multivariate step-wise logistic regression with forward selection was employed to identify the strongest associations in the entire cohort and a sub-cohort of people without falls in the year prior to baseline.RESULTS:
The Pants-sign was univariably associated with a future fall (ORâ=â2.406, 95% CI [1.313-4.409], pâ=â0.004]), but was not an independent predictor in the multivariate logistic regression; predictors were higher MDS-UPDRS part III scores (ORâ=â1.088, 95% CI [1.056-1.121], pâ<â0.001] and history of falls (ORâ=â5.696, 95% CI [2.650-12.243], p≤0.001]. For the sub-cohort of people without falls in the previous year (nâ=â189), the Pants-sign was not associated with future falls.CONCLUSIONS:
The Pants-sign is simple to assess and is associated with future falling in PD but is not an independent predictor.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Doença de Parkinson
/
Transtornos Neurológicos da Marcha
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article