Antipyretic activity of the hydro-alcoholic extract of Artemisia absinthium L. as a standalone and as an adjuvant with barley water against yeast-induced pyrexia in albino Wistar rats.
J Complement Integr Med
; 21(1): 46-52, 2024 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-38109312
ABSTRACT
OBJECTIVES:
In Unani medicine, a comprehensive treatment plan has been delineated to deal with febrile illnesses using herbal drugs along with modified dietetics, which stands as a promising area of research. The present study was aimed at evaluating the antipyretic activity of the HAE of Artemisia absinthium L. whole plant as a standalone and as an adjuvant with barley water in an animal model of pyrexia to validate the age-old Unani principle of the treatment.METHODS:
The pyrexia was induced in all the groups except the plain control using Brewer's yeast. Group II did not receive any treatment, while group III received crocin, group IV received HAE of A. absinthium, group V administered Ma al-Sha'ir, and group VI was treated with the HAE of A. absinthium along with Ma al-Sha'ir by oral route. The rectal temperature of each rat was recorded at '0'â¯h, 30â¯min, 60â¯min, and 180â¯min.RESULTS:
The mean rectal temperature of group III went down from 101.82±0.20⯰F to 100.4±0.57⯰F over the period of (0-180) minutes, whereas the mean temperature in group IV went down from 102.45±0.60⯰F to 100.14±0.57⯰F. The mean rectal temperature of group V decreased from 100.62±0.11⯰F to 99.55±0.51⯰F, while the mean rectal temperature of group VI went down from 101.95±0.1⯰F to 97.7±0.11⯰F.CONCLUSIONS:
It is concluded that the HAE of A. absinthium L. as a standalone and along with Ma al Sha'ir showed excellent antipyretic activity as compared to the standard drug in an animal model.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Hordeum
/
Artemisia absinthium
/
Antipiréticos
Limite:
Animals
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article