Fulvanines J-K, two rare lactam pyrrole alkaloids from Hemerocallis fulva.
Chem Biodivers
; 21(2): e202301672, 2024 Feb.
Article
em En
| MEDLINE
| ID: mdl-38116924
ABSTRACT
Two rare jatropham lactam derivatives, named as fulvanines J-K (1-2), together with six known pyrrole alkaloids, 5,5'-oxydi(3-methyl-3-pyrrolin-2-one) (3), (-)-5-hydroxy-3-methyl-3-pyrrolin-2-one (jatropham) (4), (±)-5-O-methyljatropham (5), perlolyrine (6), butyl-2-formyl-5-(hydroxymethyl)-1H-pyrrole-1-butanoate (7), and hemerocallisamine II (8), were isolated from the flower of Hemerocallis fulva. Their structures were elucidated on the basis of spectroscopic methods and compared with the NMR spectra data in the literature. All compounds were evaluated for their anti-complementary activity inâ
vitro, and compounds 1, 4, and 6 exhibited anti-complement effect with CH50 values from 0.61 to 1.42â
mM.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Hemerocallis
/
Alcaloides
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article