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Precision-cut lung slices as an ex vivo model to study Pneumocystis murina survival and antimicrobial susceptibility.
Munyonho, Ferris T; Clark, Robert D E; Lin, Dong; Khatun, Mst Shamima; Pungan, Dora; Dai, Guixiang; Kolls, Jay K.
Afiliação
  • Munyonho FT; Center for Translational Research in Infection and Inflammation Tulane School of Medicine, New Orleans, Louisiana, USA.
  • Clark RDE; Center for Translational Research in Infection and Inflammation Tulane School of Medicine, New Orleans, Louisiana, USA.
  • Lin D; Center for Translational Research in Infection and Inflammation Tulane School of Medicine, New Orleans, Louisiana, USA.
  • Khatun MS; Center for Translational Research in Infection and Inflammation Tulane School of Medicine, New Orleans, Louisiana, USA.
  • Pungan D; Center for Translational Research in Infection and Inflammation Tulane School of Medicine, New Orleans, Louisiana, USA.
  • Dai G; Center for Translational Research in Infection and Inflammation Tulane School of Medicine, New Orleans, Louisiana, USA.
mBio ; 15(1): e0146423, 2024 Jan 16.
Article em En | MEDLINE | ID: mdl-38117035
ABSTRACT
IMPORTANCE Our study reveals the potential of precision-cut lung slices as an ex vivo platform to study the growth/survival of Pneumocystis spp. that can facilitate the development of new anti-fungal drugs.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pneumocystis / Pneumonia por Pneumocystis / Anti-Infecciosos Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pneumocystis / Pneumonia por Pneumocystis / Anti-Infecciosos Idioma: En Ano de publicação: 2024 Tipo de documento: Article