Your browser doesn't support javascript.
loading
The case of the missing Ks: Base editor screen to assess cellular fitness at single lysines.
Gopala Krishna, Varun; Gautsch, Verena Gudrun; D'Angiolella, Vincenzo.
Afiliação
  • Gopala Krishna V; MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DS, UK.
  • Gautsch VG; MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DS, UK.
  • D'Angiolella V; MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DS, UK. Electronic address: vincenzo.dangiolella@oncology.ox.ac.uk.
Mol Cell ; 83(24): 4442-4444, 2023 Dec 21.
Article em En | MEDLINE | ID: mdl-38134884
ABSTRACT
In this issue of Molecular Cell, Bao et al.1 set out to elucidate "functional lysines" in the genome using adenine base editors. The study reveals several cases of alteration of functions that previous canonical CRISPR-Cas9 screens were unable to detect.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistemas CRISPR-Cas / Edição de Genes Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sistemas CRISPR-Cas / Edição de Genes Idioma: En Ano de publicação: 2023 Tipo de documento: Article