Current challenges in acute bacterial skin infection management.
Curr Opin Infect Dis
; 37(2): 71-79, 2024 04 01.
Article
em En
| MEDLINE
| ID: mdl-38179868
ABSTRACT
PURPOSE OF REVIEW There are aspects of skin and soft tissue infections (SSTIs) that remain unresolved, such as current numbers, classification criteria, how best to define severity and predict the outcome, what diagnostic tests to perform, what new treatment options are available, or what the duration of antibiotic treatment should be. We have reviewed the literature over the last 18âmonths to clarify these issues and provide our opinion. RECENT FINDINGS:
SSTIs are common and among the top 10 most frequent infections worldwide. They represent a burden on the healthcare system and have a major impact on the quality of life of patients. Regarding classification, the Infectious Diseases Society of America (IDSA) provides a practical guide that distinguishes between uncomplicated and complicated infections, acute and chronic wound infections, and necrotising and nonnecrotizing infections based on skin extension and tissue necrosis. With new microbiological and imaging diagnostic techniques, SSTIs can now be better diagnosed. New PCR techniques are available, and mass spectrometry can be applied to samples collected in liquid transport media. Moreover, new treatment methods such as photodynamic therapy, reactive oxygen, and phages are emerging. SSTI patients can be treated with shorter antibiotic courses if they receive an active drug with good tissue penetration. Antibiotic treatment in necrotizing infections can be shortened to 48âh after the last debridement.SUMMARY:
SSTIs remain a challenge regarding rapid and accurate diagnosis and clinical management.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Dermatopatias Bacterianas
/
Infecções dos Tecidos Moles
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article