The supportive use of photobiomodulation on salivary glands: a narrative review and meta-analysis.
Eur Arch Otorhinolaryngol
; 281(6): 2793-2805, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38189964
ABSTRACT
PURPOSE:
Radiotherapy is one of the main strategies used in the treatment of cancer patients and it can cause early or late xerostomia and/or hyposalivation. Therapeutic management of xerostomia includes oral hygiene, sialogenic agents among others.METHODS:
This study reviews the use of extra-oral salivary glands photobiomodulation in treating xerostomia and/or hyposalivation after radiotherapy and performs a meta-analysis of this data.RESULTS:
After a broad search of the literature, eight clinical studies were selected.DISCUSSION:
In a safe way, the studies found that extra-oral stimulation of the salivary glands has benefits in the hyposalivation and changes in salivary flow resulting from lesions by radiotherapy. A meta-analysis found significant values in pain comparing the pre- and post-treatment moments (MD - 3.02, I2 95%, IC - 5.56; - 0.48) and for stimulated salivary flow at 30 days after the end of radiotherapy (MD 2.90, I2 95%, IC 1.96; 3.84).CONCLUSION:
The most promising parameters comprise wavelengths between 630 and 830 nm, radiant exposure from 2 to 10 J/cm2, two-to-three times a week, before the radiotherapy damage, and homogeneously in the glands. Therefore, Light-Emitting Diode (LED) stimulation of larger areas than the punctual stimulation of small millimeters of the Low-Level Laser Therapy (LLLT) appears to be promising.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Glândulas Salivares
/
Xerostomia
/
Terapia com Luz de Baixa Intensidade
Tipo de estudo:
Systematic_reviews
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article