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Characterizing Gabapentinoid Use Among Patients With Isolated Low Back Pain.
Maloy, Gwyneth C; Halperin, Scott J; Ratnasamy, Philip P; Grauer, Jonathan N.
Afiliação
  • Maloy GC; Department of Orthopaedics & Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
  • Halperin SJ; Department of Orthopaedics & Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
  • Ratnasamy PP; Department of Orthopaedics & Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
  • Grauer JN; Department of Orthopaedics & Rehabilitation, Yale School of Medicine, New Haven, CT, USA.
Global Spine J ; : 21925682231224390, 2024 Jan 25.
Article em En | MEDLINE | ID: mdl-38270402
ABSTRACT
STUDY

DESIGN:

Retrospective cohort study.

OBJECTIVES:

Gabapentinoids have been increasingly studied as a non-narcotic option for neuropathic and postoperative pain. However, there is evidence suggesting that off-label use of these medications for the treatment of isolated LBP is not effective. The purpose of the current study was to evaluate prescription patterns for gabapentinoids among patients with isolated low back pain.

METHODS:

Adult patients with LBP were abstracted from the 2019 M91Ortho PearlDiver dataset using International Classification of Diseases (ICD-10) code M54.5. Patients were excluded if they had a diagnosis of neurologic symptoms, history of spinal surgery, spinal fracture, or conditions for which gabapentinoids are FDA approved. Gabapentinoid and narcotic prescriptions within one year of LBP diagnosis were identified. Patient characteristics and prescriber specialty were extracted from the dataset and predictors of gabapentinoid prescriptions were determined using univariate and multivariate analyses.

RESULTS:

Among the 1,158,875 isolated LBP patients, gabapentinoids were prescribed for 11%, narcotics for 8%, and both for 3%. The most common prescriber specialties included primary care physicians (45%), nurse practitioners (15%), and pain management physicians (5%). Independent predictors of gabapentinoid prescriptions included female sex, region of the country, and insurance type (P-values <.001).

CONCLUSIONS:

Of nearly 1.2 million patients with isolated LBP, 14.2% were prescribed gabapentinoids within one year of their LBP diagnosis. Patient characteristics predictive of receiving gabapentinoids were predominantly non-clinical factors.
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2024 Tipo de documento: Article