Pragmatic Adaptive Trial for Respiratory Infection in Children (PATRIC) Clinical Registry protocol.
BMJ Open
; 14(1): e074308, 2024 01 25.
Article
em En
| MEDLINE
| ID: mdl-38272557
ABSTRACT
INTRODUCTION:
Acute respiratory infections (ARI) are the most common cause of paediatric hospitalisation. There is an urgent need to address ongoing critical knowledge gaps in ARI management. The Pragmatic Adaptive Trial for Respiratory Infections in Children (PATRIC) Clinical Registry will evaluate current treatments and outcomes for ARI in a variety of paediatric patient groups. The registry will provide a platform and data to inform a number of PATRIC clinical trials, testing various interventions in ARI treatment and management to optimise paediatric ARI care. METHODS ANDANALYSIS:
The PATRIC Clinical Registry is a single-centre, prospective observational registry recruiting from a tertiary paediatric Emergency Department in Western Australia. Through characterising demographic, clinical, treatment and outcome data, the PATRIC Clinical Registry will improve our understanding of antibiotic utilisation and ARI outcomes in children. ETHICS AND DISSEMINATION The PATRIC Clinical Registry is conducted in accordance with the Declaration of Helsinki, and the International Council for Harmonisation (ICH) Guidelines for Good Clinical Practice (CPMP/ICH/13595) July 1996. Approval is provided by the Child and Adolescent Health Service Human Research Ethics Committee (HREC). Study results will be communicated by presentation and publication (HREC RGS0000003078.) TRIAL REGISTRATION NUMBER Australian New Zealand Clinical Trials Registry (ANZCTR) ACTRN12619000903189. UTN U1111-1231-3365.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções Respiratórias
Tipo de estudo:
Clinical_trials
/
Guideline
/
Observational_studies
Limite:
Adolescent
/
Child
/
Humans
País como assunto:
Oceania
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article