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Mitochondrial dysfunction in NPC1-deficiency is not rescued by drugs targeting the glucosylceramidase GBA2 and the cholesterol-binding proteins TSPO and StARD1.
Wheeler, Simon; Bhardwaj, Meenakshi; Kenyon, Victor; Ferraz, Maria J; Aerts, Johannes M F G; Sillence, Dan J.
Afiliação
  • Wheeler S; Leicester School of Pharmacy, De Montfort University, Leicester, UK.
  • Bhardwaj M; Leicester School of Pharmacy, De Montfort University, Leicester, UK.
  • Kenyon V; Atomwise, San Francisco, CA, USA.
  • Ferraz MJ; Leiden Institute of Chemistry, Leiden University, The Netherlands.
  • Aerts JMFG; Leiden Institute of Chemistry, Leiden University, The Netherlands.
  • Sillence DJ; Leicester School of Pharmacy, De Montfort University, Leicester, UK.
FEBS Lett ; 598(4): 477-484, 2024 Feb.
Article em En | MEDLINE | ID: mdl-38302739
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Doenças Mitocondriais / Doença de Niemann-Pick Tipo C Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Doenças Mitocondriais / Doença de Niemann-Pick Tipo C Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article