Out with the old, in with the new: Pioneer transcription factors as activators and repressors of lineage specification genes.
Mol Cell
; 84(3): 411-412, 2024 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-38307001
ABSTRACT
In this issue of Molecular Cell, Matsui et al.1 examine lineage determination by pioneer transcription factors, finding that they control cell fate in cooperation with PRDM family members by repressing alternative-lineage and precocious gene expression through establishment of bivalent enhancers.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fatores de Transcrição
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article