Chromosome level genome assembly of the Etruscan shrew Suncus etruscus.
Sci Data
; 11(1): 176, 2024 Feb 07.
Article
em En
| MEDLINE
| ID: mdl-38326333
ABSTRACT
Suncus etruscus is one of the world's smallest mammals, with an average body mass of about 2 grams. The Etruscan shrew's small body is accompanied by a very high energy demand and numerous metabolic adaptations. Here we report a chromosome-level genome assembly using PacBio long read sequencing, 10X Genomics linked short reads, optical mapping, and Hi-C linked reads. The assembly is partially phased, with the 2.472 Gbp primary pseudohaplotype and 1.515 Gbp alternate. We manually curated the primary assembly and identified 22 chromosomes, including X and Y sex chromosomes. The NCBI genome annotation pipeline identified 39,091 genes, 19,819 of them protein-coding. We also identified segmental duplications, inferred GO term annotations, and computed orthologs of human and mouse genes. This reference-quality genome will be an important resource for research on mammalian development, metabolism, and body size control.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Musaranhos
/
Cromossomos
Limite:
Animals
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article