[Salvage lymphadenectomy for recurrent prostate cancer]. / Salvage-Lymphadenektomie beim Prostatakarzinom.
Urologie
; 63(3): 234-240, 2024 Mar.
Article
em De
| MEDLINE
| ID: mdl-38329484
ABSTRACT
Prostate-specific membrane antigen (PSMA)-based positron emission tomography (PET) imaging allows early detection of metastases in patients with biochemical recurrence. Salvage lymphadenectomy became a widely used method of metastasis-directed treatment. Retrospective analyses show that a low prostate-specific antigen (PSA) value and presence of no more than two affected lymph nodes within the pelvis are factors associated with a good outcome. In all, 40-80% of patients achieve a complete biochemical response with a mean time without biochemical recurrence of 8 months and a prolonged treatment-free interval. About 10% of patients with a complete biochemical response will live without recurrence after 10 years. The utilization of PSMA-radioguided surgery increases the likelihood of intraoperative detection of suspicious affected lymph nodes. Complications can mostly be avoided by prudent patient selection and surgical expertise.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
Recidiva Local de Neoplasia
Tipo de estudo:
Screening_studies
Limite:
Humans
/
Male
Idioma:
De
Ano de publicação:
2024
Tipo de documento:
Article