Combretum micranthum G. Don (Combretaceae): A Review on Traditional Uses, Phytochemistry, Pharmacology and Toxicology.
Chem Biodivers
; 21(5): e202301606, 2024 May.
Article
em En
| MEDLINE
| ID: mdl-38353648
ABSTRACT
Combretum micranthum (Combretaceae) is a medicinal plant widely known and used in Africa to treat a variety of conditions such as diabetes, fever, coughs, bronchitis, diarrhea, pain, malaria and liver disorders, among others. Due to its wide traditional use, in this review, published scientific reports on its composition and pharmacological properties were explored by conducting a literature search of databases. To date, 155 organic compounds including 34 flavonoids, 16 phenolic acids, 14 alkaloids, 15 fatty acids, 14 terpenoids/steroids, 24 amino acids, 8 carbohydrate substances and 30 other organic compounds have been identified from this plant. In addition to these organic compounds, 6 minerals (potassium nitrate, calcium, magnesium, potassium, sodium, iron and zinc) have also been reported. In vitro and inâ
vivo studies have shown that these phytochemicals and plant extracts have a wide range of pharmacological potential, including antibacterial, antiviral, antioxidant, antidiabetic, anti-inflammatory, analgesic, antihypertensive, nephroprotective, hepatoprotective, anxiolytic, anti-cholinesterase and antidiarrheal activities. Additionally, no harmful effects have been revealed through studies. Thus, this study could constitute a valuable reference for the valorization of C. micranthum in the pharmaceutical industry.
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Base de dados:
MEDLINE
Assunto principal:
Compostos Fitoquímicos
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article