Your browser doesn't support javascript.
loading
Characterizing induced pluripotent stem cells and derived cardiomyocytes: insights from nano scale mass measurements and mechanical properties.
Turnbull, Irene C; Gaitas, Angelo.
Afiliação
  • Turnbull IC; Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai New York NY 10029 USA irene.turnbull@mssm.edu.
  • Gaitas A; The Estelle and Daniel Maggin Department of Neurology, Icahn School of Medicine at Mount Sinai New York NY 10029 USA angelo.gaitas@mssm.edu.
Nanoscale Adv ; 6(4): 1059-1064, 2024 Feb 13.
Article em En | MEDLINE | ID: mdl-38356620
ABSTRACT
Our study reveals that the nano-mechanical measures of elasticity and cell mass change significantly through induced pluripotent stem cell (iPSC) differentiation to cardiomyocytes, providing a reliable method to evaluate such processes. The findings support the importance of identifying these properties, and highlight the potential of AFM for comprehensive characterization of iPSC at the nanoscale.

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2024 Tipo de documento: Article