Sex differences and racial/ethnic disparities in the presentation and treatment of medullary thyroid cancer.
Am J Surg
; 234: 19-25, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-38365554
ABSTRACT
BACKGROUND:
This study assessed for disparities in the presentation and management of medullary thyroid cancer (MTC).METHODS:
Patients with MTC (2010-2020) were identified from the National Cancer Database. Differences in disease presentation and likelihood of guideline-concordant surgical management (total thyroidectomy and resection of ≥1 lymph node) were assessed by sex and race/ethnicity.RESULTS:
Of 6154 patients, 68.2% underwent guideline-concordant surgery. Tumors >4 âcm were more likely in men (vs. women OR 2.47, p â< â0.001) and Hispanic patients (vs. White patients OR 1.52, p â= â0.001). Non-White patients were more likely to have distant metastases (Black OR 1.63, p â= â0.002; Hispanic OR 1.44, p â= â0.038) and experienced longer time to surgery (Black HR 0.66, p â< â0.001; Hispanic HR 0.71, p â< â0.001). Black patients were less likely to undergo guideline-concordant surgery (OR 0.70, p â= â0.022).CONCLUSIONS:
Male and non-White patients with MTC more frequently present with advanced disease, and Black patients are less likely to undergo guideline-concordant surgery.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Tireoidectomia
/
Neoplasias da Glândula Tireoide
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Carcinoma Neuroendócrino
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Disparidades em Assistência à Saúde
Limite:
Adult
/
Aged
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Female
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Humans
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Male
/
Middle aged
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article