Milestone Papers on Signal Transduction Mechanisms of Hypertension and Its Complications.
Hypertension
; 81(5): 977-990, 2024 May.
Article
em En
| MEDLINE
| ID: mdl-38372140
ABSTRACT
To celebrate 100 years of American Heart Association-supported cardiovascular disease research, this review article highlights milestone papers that have significantly contributed to the current understanding of the signaling mechanisms driving hypertension and associated cardiovascular disorders. This article also includes a few of the future research directions arising from these critical findings. To accomplish this important mission, 4 principal investigators gathered their efforts to cover distinct yet intricately related areas of signaling mechanisms pertaining to the pathogenesis of hypertension. The renin-angiotensin system, canonical and novel contractile and vasodilatory pathways in the resistance vasculature, vascular smooth muscle regulation by membrane channels, and noncanonical regulation of blood pressure and vascular function will be described and discussed as major subjects.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Sistema Cardiovascular
/
Hipertensão
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article