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Novel modifications of PARP inhibitor veliparib increase PARP1 binding to DNA breaks.
Velagapudi, Uday Kiran; Rouleau-Turcotte, Élise; Billur, Ramya; Shao, Xuwei; Patil, Manisha; Black, Ben E; Pascal, John M; Talele, Tanaji T.
Afiliação
  • Velagapudi UK; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, U.S.A.
  • Rouleau-Turcotte É; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Canada H3T 1J4.
  • Billur R; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6059, U.S.A.
  • Shao X; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, U.S.A.
  • Patil M; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, U.S.A.
  • Black BE; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6059, U.S.A.
  • Pascal JM; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Canada H3T 1J4.
  • Talele TT; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, U.S.A.
Biochem J ; 481(6): 437-460, 2024 Mar 20.
Article em En | MEDLINE | ID: mdl-38372302
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Poli(ADP-Ribose) Polimerases / Antineoplásicos Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Poli(ADP-Ribose) Polimerases / Antineoplásicos Idioma: En Ano de publicação: 2024 Tipo de documento: Article