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In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection.
Tan, Chin Wee; Chen, Jinjin; Liu, Ning; Bhuva, Dharmesh D; Blick, Tony; Monkman, James; Cooper, Caroline; Kharbanda, Malvika; Feher, Kristen; Phipson, Belinda; Killingbeck, Emily E; Pan, Liuliu; Kim, Youngmi; Liang, Yan; Nam, Andy; Leon, Michael; Souza-Fonseca-Guimaraes, Paulo; Nagashima, Seigo; Camargo Martins, Ana Paula; Machado-Souza, Cleber; de Noronha, Lucia; Tang, Benjamin; Short, Kirsty; Fraser, John; Belz, Gabrielle T; Souza-Fonseca-Guimaraes, Fernando; Kulasinghe, Arutha; Davis, Melissa J.
Afiliação
  • Tan CW; Division of Bioinformatics, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia; Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, VIC, 3010, Australia; Frazer Institute, Faculty of Medicine, The Un
  • Chen J; Division of Bioinformatics, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia; Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, VIC, 3010, Australia.
  • Liu N; Division of Bioinformatics, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia; Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, VIC, 3010, Australia; South Australian ImmunoGENomics Cancer Instit
  • Bhuva DD; Division of Bioinformatics, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia; Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, VIC, 3010, Australia; South Australian ImmunoGENomics Cancer Instit
  • Blick T; Frazer Institute, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.
  • Monkman J; Frazer Institute, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.
  • Cooper C; Frazer Institute, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia; Princess Alexandra Hospital, Woolloongabba, QLD, Australia.
  • Kharbanda M; Division of Bioinformatics, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia; Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, VIC, 3010, Australia; South Australian ImmunoGENomics Cancer Instit
  • Feher K; Division of Bioinformatics, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia; Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, VIC, 3010, Australia; South Australian ImmunoGENomics Cancer Instit
  • Phipson B; Division of Bioinformatics, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia; Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, VIC, 3010, Australia.
  • Killingbeck EE; Nanostring Technologies, Inc, Seattle, WA, USA.
  • Pan L; Nanostring Technologies, Inc, Seattle, WA, USA.
  • Kim Y; Nanostring Technologies, Inc, Seattle, WA, USA.
  • Liang Y; Nanostring Technologies, Inc, Seattle, WA, USA.
  • Nam A; Nanostring Technologies, Inc, Seattle, WA, USA.
  • Leon M; Nanostring Technologies, Inc, Seattle, WA, USA.
  • Souza-Fonseca-Guimaraes P; Pontifícia Universidade Católica do Paraná, PUCPR, Curitiba, Paraná, Brazil.
  • Nagashima S; Laboratório de Patologia Experimental, PPGCS da PUCPR, Curitiba, Brazil.
  • Camargo Martins AP; Laboratório de Patologia Experimental, PPGCS da PUCPR, Curitiba, Brazil.
  • Machado-Souza C; Faculdades Pequeno Príncipe (FPP), Instituto de Pesquisa Pelé Pequeno Príncipe (IPPPP), R. Silva Jardim, 1632-ÁguaVerde, Curitiba, 80230-020, PR, Brazil.
  • de Noronha L; Laboratório de Patologia Experimental, PPGCS da PUCPR, Curitiba, Brazil.
  • Tang B; Westmead Institute for Medical Research, Sydney, Australia.
  • Short K; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.
  • Fraser J; Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia; Faculty of Medicine University of Queensland, Brisbane, QLD, Australia; St Andrew's War Memorial Hospital, UnitingCare, Spring Hill, QLD, Australia.
  • Belz GT; Frazer Institute, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.
  • Souza-Fonseca-Guimaraes F; Frazer Institute, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia.
  • Kulasinghe A; Frazer Institute, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia. Electronic address: arutha.kulasinghe@uq.edu.au.
  • Davis MJ; Division of Bioinformatics, Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, 3052, Australia; Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Parkville, VIC, 3010, Australia; Frazer Institute, Faculty of Medicine, The Un
EBioMedicine ; 101: 105016, 2024 Mar.
Article em En | MEDLINE | ID: mdl-38377798
ABSTRACT
The utilization of single-cell resolved spatial transcriptomics to delineate immune responses during SARS-CoV-2 infection was able to identify M1 macrophages to have elevated expression of IFI27 in areas of infection.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: COVID-19 Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: COVID-19 Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article