Synthesis, antibacterial activity, and 3D-QASR studies of matrine-indole derivatives as potential antibiotics.

Li, Yufang; Kowah, Jamal A H; Jiang, Meiyan; Wu, Yaqing; Wang, Lisheng; Yang, Fangfang

Li, Yufang; Kowah, Jamal A H; Jiang, Meiyan; Wu, Yaqing; Wang, Lisheng; Yang, Fangfang.

Afiliação

Li Y; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China. Electronic address: liyufang6880@163.com.
Kowah JAH; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China.
Jiang M; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China.
Wu Y; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China.
Wang L; School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004, China; Guangxi Key Laboratory of Special Biomedicine, School of Medicine, Guangxi University, Nanning 530004, China. Electronic address: w_lsheng@163.com.
Yang F; Guangxi - ASEAN Food Inspection and Testing Center, Nanning 530021, China.

Bioorg Med Chem Lett ; 102: 129671, 2024 Apr 01.

Article em En | MEDLINE | ID: mdl-38387690

Assuntos

Antibacterianos; Matrinas; Antibacterianos/química; Staphylococcus aureus; Escherichia coli; Simulação de Acoplamento Molecular; Testes de Sensibilidade Microbiana; Indóis/farmacologia

Palavras-chave

3D-QSAR; Antibacterial; Matrine-indole derivatives; Molecular docking; Synthesis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Matrinas / Antibacterianos Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Matrinas / Antibacterianos Idioma: En Ano de publicação: 2024 Tipo de documento: Article