Thyroid transcriptomic profiling reveals the differential regulation of lncRNA and mRNA related to prolificacy in small tail han sheep with FecB BB genotype.
Anim Biotechnol
; 35(1): 2312393, 2024 Nov.
Article
em En
| MEDLINE
| ID: mdl-38421365
ABSTRACT
BACKGROUND:
The thyroid gland is an important endocrine gland in animals that secretes thyroid hormones and acts on various organs throughout the body. lncRNAs are long non-coding RNAs that play an important role in animal reproduction; however, there is a lack of understanding of their expression patterns and potential roles in the thyroid gland of the Small Tail Han (STH) sheep. In this study, we used RNA-Seq technology to examine the transcriptome expression pattern of the thyroid from the luteal phase (LP) and follicular phase (FP) of FecB BB (MM) STH sheep.RESULTS:
We identified a total of 122 and 1287 differential expression lncRNAs (DELs) and differential expression mRNAs (DEGs), respectively, which were significantly differentially expressed. These DELs target genes and DEGs can be enriched in several signalling pathways related to the animal reproduction process.CONCLUSIONS:
The expression profiles of DELs and DEGs in thyroid glands provide a more comprehensive resource for elucidating the reproductive regulatory mechanisms of STH sheep.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Glândula Tireoide
/
RNA Longo não Codificante
Limite:
Animals
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article