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Simultaneous determination of BGT-002 and its acyl glucuronide metabolite ZM326E-M2 in human plasma by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study.
Zhu, Xueran; Cui, Shumin; Liu, Xinjing; Zhang, Mei; Xie, Zhifu; Li, Wei; Li, Jingya; Nan, Fajun; Zhang, Yangming; Zhan, Yan; Chen, Xiaoyan.
Afiliação
  • Zhu X; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, PR China.
  • Cui S; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, PR China.
  • Liu X; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, PR China.
  • Zhang M; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, PR China.
  • Xie Z; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, PR China.
  • Li W; Burgeon Therapeutics Co., Ltd., Shanghai 201203, PR China.
  • Li J; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, PR China.
  • Nan F; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, PR China.
  • Zhang Y; Burgeon Therapeutics Co., Ltd., Shanghai 201203, PR China. Electronic address: ymzhang@burgeon-cn.com.
  • Zhan Y; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, PR China. Electronic address: yzhan@simm.ac.cn.
  • Chen X; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, PR China; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing 210023, PR China. Electronic address: xychen@simm.ac.cn.
J Pharm Biomed Anal ; 243: 116056, 2024 Jun 15.
Article em En | MEDLINE | ID: mdl-38428245
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glucuronídeos / Espectrometria de Massas em Tandem Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glucuronídeos / Espectrometria de Massas em Tandem Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article