Surgical outcomes and healthcare expenditures among patients with dementia undergoing major surgery.
World J Surg
; 48(5): 1075-1083, 2024 05.
Article
em En
| MEDLINE
| ID: mdl-38436547
ABSTRACT
BACKGROUND:
We sought to define surgical outcomes among elderly patients with Alzheimer's disease and related dementias (ADRD) following major thoracic and gastrointestinal surgery.METHODS:
A retrospective cohort study was used to identify patients who underwent coronary artery bypass grafting (CABG), abdominal aortic aneurysm (AAA) repair, pneumonectomy, pancreatectomy, and colectomy. Individuals were identified from the Medicare Standard Analytic Files and multivariable regression was utilized to assess the association of ADRD with textbook outcome (TO), expenditures, and discharge disposition.RESULTS:
Among 1,175,010 Medicare beneficiaries, 19,406 (1.7%) patients had a preoperative diagnosis of ADRD (CABG n = 1,643, 8.5%; AAA repair n = 5,926, 30.5%; pneumonectomy n = 590, 3.0%; pancreatectomy n = 181, 0.9%; and colectomy n = 11,066, 57.0%). After propensity score matching, patients with ADRD were less likely to achieve a TO (ADRD 31.2% vs. no ADRD 40.1%) or be discharged to home (ADRD 26.7% vs. no ADRD 46.2%) versus patients who did not have ADRD (both p < 0.001). Median index surgery expenditures were higher among patients with ADRD (ADRD $28,815 [IQR $14,333-$39,273] vs. no ADRD $27,101 [IQR $13,433-$38,578]; p < 0.001) (p < 0.001). On multivariable analysis, patients with ADRD had higher odds of postoperative complications (OR 1.32, 95% CI 1.25-1.40), extended length-of-stay (OR 1.26, 95% CI 1.21-1.32), 90-day readmission (OR 1.37, 95% CI 1.31-1.43), and 90-day mortality (OR 1.76, 95% CI 1.66-1.86) (all p < 0.001).CONCLUSION:
Preoperative diagnosis of ADRD was an independent risk factor for poor postoperative outcomes, discharge to non-home settings, as well as higher healthcare expenditures. These data should serve to inform discussions and decision-making about surgery among the growing number of older patients with cognitive deficits.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Gastos em Saúde
/
Demência
Limite:
Aged
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Aged80
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Female
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Humans
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Male
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article