Amplitude-integrated electroencephalography showed no differences in cerebral activity between preterm singletons and twins in the first 4 weeks of life.
Acta Paediatr
; 113(6): 1356-1363, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38441276
ABSTRACT
AIM:
Genetic influences on cerebral activity have been described previously, but data are scarce in preterms. We aimed to investigate whether a genetic influence causes amplitude-integrated electroencephalography (aEEG) signals to differ between singletons and twin preterm newborns.METHODS:
This was a retrospective single-centre study conducted at Innsbruck Medical University Hospital, Austria. Preterm infants born before 32 weeks of gestation between 6 November 2010 and 6 December 2022 were eligible for the study. The aEEG was analysed for the total maturation score, its component scores and the number of sleep-wake cycles per hour.RESULTS:
We enrolled 240 preterm twin infants (57.5% male) with a mean gestational age of 30 (range 24-32) weeks and a mean birth weight of 1324 (range 600-2116) grams. We compared 240 singleton matched preterms. No differences were found between preterm singletons and twin preterm infants regarding the total maturation and component scores, or the number of sleep-wake cycles. aEEG showed no difference between monozygotic and dizygotic twins.CONCLUSION:
Compared to singletons, twin infants born preterm showed no differences in aEEG signals in the first 4 weeks of life. Future studies should include more complex non-invasive functional neuroimaging methods to gain more insight into this important topic.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Recém-Nascido Prematuro
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Eletroencefalografia
Limite:
Female
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Humans
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Male
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Newborn
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article