Revisiting the Modularity-Disease transmission Link: Uncovering the importance of intra-modular structure.

ABSTRACT

Studies have shown that the internal structure of modules is hardly important for the spread of epidemics. However, most of these studies have assumed that intra-module connectivity and inter-module connectivity do not affect each other. In reality, changes in the internal structure of modules may affect inter-module links and thus change the modularity of the entire network. Therefore, we have developed a theoretical network model with adjustable modularity to investigate the impact of this situation on disease transmission. Our findings indicate that the intra-module structure plays a crucial role in disease outbreaks. Changes in intra-module structure lead to significant numerical changes in peak prevalence and duration of disease. This implies that the potential impact of changes in exposure patterns within modules should also be considered when investigating the exact impact of modular social networks on disease burden.