[Use of murine models for the study of obstructive sleep apnea syndrome in Down syndrome]. / Utilisation des modèles murins pour l'étude du syndrome d'apnées obstructives du sommeil dans le syndrome de Down.
Rev Mal Respir
; 41(4): 279-282, 2024 Apr.
Article
em Fr
| MEDLINE
| ID: mdl-38461093
ABSTRACT
Down syndrome (DS), or trisomy 21, is a genetic disorder caused by the presence of an extra copy of chromosome 21, leading to various characteristic physical features as well as developmental and cognitive delays. Obstructive sleep apnea syndrome (OSAS) is a common disorder in both adult and pediatric patients with DS. Several characteristics of DS may contribute to the development or worsening of OSAS. Numerous murine models of DS exist. A number of studies have explored apneas and the risk of upper airway obstruction in these models, but up until now, only in adulthood.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Síndrome de Down
/
Apneia Obstrutiva do Sono
Limite:
Adult
/
Animals
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Child
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Humans
Idioma:
Fr
Ano de publicação:
2024
Tipo de documento:
Article