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Innovative Encapsulation Strategies for Food, Industrial, and Pharmaceutical Applications.
Aanniz, Tarik; El Omari, Nasreddine; Elouafy, Youssef; Benali, Taoufiq; Zengin, Gokhan; Khalid, Asaad; Abdalla, Ashraf N; Sakran, Ashraf M; Bouyahya, Abdelhakim.
Afiliação
  • Aanniz T; Biotechnology Laboratory (MedBiotech), Bioinova Research Center, Rabat Medical and Pharmacy School, Mohammed V University in Rabat, Rabat, 10100, Morocco.
  • El Omari N; High Institute of Nursing Professions and Health Techniques of Tetouan, Tetouan, Morocco.
  • Elouafy Y; Laboratory of Histology, Embryology, and Cytogenetic, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Rabat, 10100, Morocco.
  • Benali T; Laboratory of Materials, Nanotechnology and Environment LMNE, Faculty of Sciences, Mohammed V University in Rabat, Rabat BP, 1014, Morocco.
  • Zengin G; Environment and Health Team, Polydisciplinary Faculty of Safi, Cadi Ayyad University, Marrakech, 46030, Morocco.
  • Khalid A; Department of Biology, Science Faculty, Selcuk University, 42130, Konya, Turkey.
  • Abdalla AN; Substance Abuse and Toxicology Research Center, Jazan University, P.O. Box: 114, Jazan, 45142, Saudi Arabia.
  • Sakran AM; Medicinal and Aromatic Plants and Traditional Medicine Research Institute, National Center for Research, P. O. Box 2404, Khartoum, Sudan.
  • Bouyahya A; Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah, 21955, Saudi Arabia.
Chem Biodivers ; 21(5): e202400116, 2024 May.
Article em En | MEDLINE | ID: mdl-38462536
ABSTRACT
Bioactive metabolites obtained from fruits and vegetables as well as many drugs have various capacities to prevent or treat various ailments. Nevertheless, their efficiency, in vivo, encounter many challenges resulting in lower efficacy as well as different side effects when high doses are used resulting in many challenges for their application. Indeed, demand for effective treatments with no or less unfavorable side effects is rising. Delivering active molecules to a particular site of action within the human body is an example of targeted therapy which remains a challenging field. Developments of nanotechnology and polymer science have great promise for meeting the growing demands of efficient options. Encapsulation of active ingredients in nano-delivery systems has become as a vitally tool for protecting the integrity of critical biochemicals, improving their delivery, enabling their controlled release and maintaining their biological features. Here, we examine a wide range of nano-delivery techniques, such as niosomes, polymeric/solid lipid nanoparticles, nanostructured lipid carriers, and nano-emulsions. The advantages of encapsulation in targeted, synergistic, and supportive therapies are emphasized, along with current progress in its application. Additionally, a revised collection of studies was given, focusing on improving the effectiveness of anticancer medications and addressing the problem of antimicrobial resistance. To sum up, this paper conducted a thorough analysis to determine the efficacy of encapsulation technology in the field of drug discovery and development.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanopartículas Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanopartículas Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article