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Exploring the Diverse Biological Properties of Cannabidiol: A Focus on Plant Growth Stimulation.
Grulová, Daniela; Baranová, Beáta; Francolino, Rosaria; Elshafie, Hazem S; Kissová, Zuzana; Glovatáková, Alzbeta; De Martino, Laura; Amato, Giuseppe; Martino, Mara; Caputo, Lucia; Polito, Flavio; Manna, Francesco; Camele, Ippolito; Tkáciková, Ludmila; De Feo, Vincenzo.
Afiliação
  • Grulová D; Department of Ecology, Faculty of Humanities and Natural Sciences, University of Presov, 17. novembra 1, 08001, Presov, Slovakia.
  • Baranová B; Department of Ecology, Faculty of Humanities and Natural Sciences, University of Presov, 17. novembra 1, 08001, Presov, Slovakia.
  • Francolino R; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano, Italy.
  • Elshafie HS; School of Agricultural, Forestry, Food and Environmental Sciences, University of Basilicata, Via dell'Ateneo Lucano, 10, 85100, Potenza, Italy.
  • Kissová Z; Department of Microbiology and Immunology, University of Veterinary Medicine and Pharmacy in Kosice, 041 81, Kosice, Slovakia.
  • Glovatáková A; Department of Ecology, Faculty of Humanities and Natural Sciences, University of Presov, 17. novembra 1, 08001, Presov, Slovakia.
  • De Martino L; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano, Italy.
  • Amato G; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano, Italy.
  • Martino M; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano, Italy.
  • Caputo L; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano, Italy.
  • Polito F; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano, Italy.
  • Manna F; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano, Italy.
  • Camele I; School of Agricultural, Forestry, Food and Environmental Sciences, University of Basilicata, Via dell'Ateneo Lucano, 10, 85100, Potenza, Italy.
  • Tkáciková L; Department of Microbiology and Immunology, University of Veterinary Medicine and Pharmacy in Kosice, 041 81, Kosice, Slovakia.
  • De Feo V; Department of Pharmacy, University of Salerno, Via Giovanni Paolo II, 132, 84084, Fisciano, Italy.
Chem Biodivers ; 21(5): e202400274, 2024 May.
Article em En | MEDLINE | ID: mdl-38466647
ABSTRACT
The aim of the current study was to compare some biological activities of edible oils enriched with 10 % of cannabidiol (CBD samples) from the Slovak market. In addition, hemp, coconut, argan, and pumpkin pure oils were also examined. The study evaluated the fatty acids content, as well as antibacterial, antifungal, antioxidant, cytotoxic, and phytotoxic activities. The CBD samples presented antimicrobial activity against the tested bacterial strains at higher concentrations (10000 and 5000 mg/L) and antifungal activity against Alternaria alternata, Penicillium italicum and Aspergillus flavus. DPPH⋅ and FRAP assays showed greater activity in CBD-supplemented samples compared to pure oils and vitamin E. In cell lines (IPEC-J2 and Caco-2), a reduced cell proliferation and viability were observed after 24 hours of incubation with CBD samples. The oils showed pro-germinative effects. The tested activities were linked to the presence of CBD in the oils.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Canabidiol / Proliferação de Células / Antioxidantes Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Canabidiol / Proliferação de Células / Antioxidantes Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article