Inhibition by pesticides of prostaglandin formation in blood platelets.
Blut
; 51(1): 19-23, 1985 Jul.
Article
em En
| MEDLINE
| ID: mdl-3848334
ABSTRACT
Aggregation of human platelets was investigated after pre-incubation of platelet rich plasma with various pesticides of the carbamate type. Whereas N-methyl-carbamates (insecticides) inhibited the arachidonic acid induced aggregation, N-phenyl-carbamates (herbicides) had no effect. The influence of the different carbamates on aggregation coincided with their inhibition of thromboxane B2-formation. - DDE, a metabolite of the insecticide DDT, affected aggregation to a similar extent as N-methyl-carbamates. DDT, however, had no inhibitory activity.
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Base de dados:
MEDLINE
Assunto principal:
Plaquetas
/
Carbamatos
/
Prostaglandinas
/
DDT
/
Inseticidas
Limite:
Humans
Idioma:
En
Ano de publicação:
1985
Tipo de documento:
Article