An isolated sacral promyelocytic sarcoma in a child: A rare case report with emphasis on cytomorphology.
Diagn Cytopathol
; 52(6): E145-E149, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38494827
ABSTRACT
Myeloid sarcoma (MS) is an uncommon localized extramedullary tumor composed of immature myeloid precursor cells that can affect any organ. Promyelocytic sarcoma (PS), an extremely rare subtype of MS, is characterized by immature myeloid cells with features of acute promyelocytic leukemia (APL). We describe a case of pediatric PS that presented as a solitary sacral mass without any evidence of systemic or bone marrow involvement. The cytopathologic evaluation using touch imprint demonstrated numerous blasts with bilobed nuclei, cytoplasmic hyper-granularity, and aggregates of Auer rods, which are typical cytomorphologic features of APL. Herein, we report an extremely rare case of isolated PS in a child, emphasizing the importance of cytomorphologic evaluation, which is complemented by the findings from a comprehensive work-up.
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Base de dados:
MEDLINE
Assunto principal:
Sarcoma Mieloide
Limite:
Child
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article