Your browser doesn't support javascript.
loading
Twice-walk strategy based on three-dimensional DNA walking machine driven by duplex-specific nuclease.
Lei, Sheng; Liu, Zi; Zhang, Qidong; Li, Zezhi; Li, Gaiping; Zou, Lina; Chai, Guobi; Mao, Jian; Ye, Baoxian; Zhang, Jianxun.
Afiliação
  • Lei S; Zhengzhou Tobacco Research Institute of China National Tobacco Company, Zhengzhou 450001, P. R. China. jxzh258@163.com.
  • Liu Z; College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, P. R. China.
  • Zhang Q; Henan Key Laboratory of Biomolecular Recognition and Sensing, Henan Joint International Research Laboratory of Chemo/Biosensing and Early Diagnosis of Major Diseases, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, P. R. China.
  • Li Z; Zhengzhou Tobacco Research Institute of China National Tobacco Company, Zhengzhou 450001, P. R. China. jxzh258@163.com.
  • Li G; Zhengzhou Tobacco Research Institute of China National Tobacco Company, Zhengzhou 450001, P. R. China. jxzh258@163.com.
  • Zou L; School of Light Industry, Beijing Technology and Business University, Beijing 100048, P. R. China.
  • Chai G; College of Chemistry, Zhengzhou University, Zhengzhou 450001, P. R. China.
  • Mao J; College of Chemistry, Zhengzhou University, Zhengzhou 450001, P. R. China.
  • Ye B; Zhengzhou Tobacco Research Institute of China National Tobacco Company, Zhengzhou 450001, P. R. China. jxzh258@163.com.
  • Zhang J; Zhengzhou Tobacco Research Institute of China National Tobacco Company, Zhengzhou 450001, P. R. China. jxzh258@163.com.
Chem Commun (Camb) ; 60(28): 3778-3781, 2024 Apr 02.
Article em En | MEDLINE | ID: mdl-38494893
ABSTRACT
A twice-walk strategy based on a three-dimensional (3D) cleat-equipped DNA walking machine with a high signal amplification efficiency was investigated for ultrasensitive detection of miRNA. Impressively, addition of duplex-specific nuclease (DSN) just once drove the twice-walk strategy, making the strategy simpler. With the advantages of being simple, rapid and ultrasensitive, the biosensor offers potential for use in early clinical diagnosis.
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / MicroRNAs Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / MicroRNAs Idioma: En Ano de publicação: 2024 Tipo de documento: Article