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Catalytic Atroposelective Synthesis of Axially Chiral Heterobiaryl Oxime Ethers via the One-Step Dynamic Kinetic Condensation Reaction.
Xu, Qianqian; Jia, Jifan; Fan, Haitong; Ma, Zhifeng; Wu, Yuqing; Zhang, Yifeng; Su, Ping; Gao, Wei; Wang, Yuji; Li, Dan.
Afiliação
  • Xu Q; School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China.
  • Jia J; School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China.
  • Fan H; School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China.
  • Ma Z; School of Chemistry and Environment, Yunnan Minzu University, Kunming, Yunnan 650500, China.
  • Wu Y; School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China.
  • Zhang Y; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chi-nese Materia Medica, China Academy of Chinese Medical Science, Beijng 100700, China.
  • Su P; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chi-nese Materia Medica, China Academy of Chinese Medical Science, Beijng 100700, China.
  • Gao W; School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China.
  • Wang Y; School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China.
  • Li D; School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China.
Org Lett ; 26(12): 2403-2408, 2024 Mar 29.
Article em En | MEDLINE | ID: mdl-38502802
ABSTRACT
The catalytic atroposelective synthesis of axially chiral heterobiaryls was first developed through the direct one-step dynamic kinetic condensation reaction with the simple transformation of the C═O bond to the C═N bond, delivering a series of novel axially chiral heterobiaryl oxime ethers.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article