Lifestyle factors on the long-term survival of gastric cancer patients after radical resection: A cohort study.
J Res Med Sci
; 29: 11, 2024.
Article
em En
| MEDLINE
| ID: mdl-38524749
ABSTRACT
Background:
This retrospective cohort study aimed to evaluate the effect of lifestyle factors (e.g., smoking, drinking, physical exercise, and sleep duration) on the long-term survival of gastric cancer (GC) patients after radical resection. Materials andMethods:
GC patients after radical resection were enrolled from January 2016 to December 2017. Their baseline clinical data, lifestyle factors, and prognosis were collected. The primary endpoint was all-cause death. The relationship between the variables and survival was examined using the Cox proportional hazards model.Results:
A total of 309 patients were enrolled and 296 patients were followed up for a median of 54.0 months, with 130 confirmed deaths. Older age (>60 years) (hazard ratio [HR] 1.307, 95% confidence interval [CI] 1.056-2.161, P = 0.006), advanced tumor, node, and metastasis stage (P < 0.05), poorly pathological differentiation (HR 1.765, 95% CI 1.080-2.884, P = 0.023), history of smoking (P < 0.001), never physical exercise (HR 2.057, 95% CI 1.170-3.617, P = 0.012), long sleep duration (≥8 h) (HR 4.160, 95% CI 1.501-11.533, P = 0.006), and short sleep duration (<6 h) (HR 3.417, 95% CI 1.312-8.900, P = 0.012) were independent indicators of a poor overall survival in GC patients after radical resection.Conclusion:
Smoking cessation, proper sleep duration, and regular physical exercise habits can improve the long-term survival of GC patients after radical resection.
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article