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The heavy subunit of ferritin stimulates NLRP3 inflammasomes in hepatic stellate cells through ICAM-1 to drive hepatic inflammation.
Fernandez-Rojo, Manuel A; Pearen, Michael A; Burgess, Anita G; Ikonomopoulou, Maria P; Hoang-Le, Diem; Genz, Berit; Saggiomo, Silvia L; Nawaratna, Sujeevi S K; Poli, Maura; Reissmann, Regina; Gobert, Geoffrey N; Deutsch, Urban; Engelhardt, Britta; Brooks, Andrew J; Jones, Alun; Arosio, Paolo; Ramm, Grant A.
Afiliação
  • Fernandez-Rojo MA; QIMR Berghofer Medical Research Institute, Brisbane, Herston, QLD 4006, Australia.
  • Pearen MA; School of Medicine, University of Queensland, Brisbane, Herston, QLD 4006, Australia.
  • Burgess AG; Hepatic Regenerative Medicine Laboratory, Madrid Institute for Advanced Studies in Food, Madrid 28049, Spain.
  • Ikonomopoulou MP; University of Queensland Diamantina Institute, University of Queensland, Translational Research Institute, Brisbane, QLD 4102, Australia.
  • Hoang-Le D; QIMR Berghofer Medical Research Institute, Brisbane, Herston, QLD 4006, Australia.
  • Genz B; QIMR Berghofer Medical Research Institute, Brisbane, Herston, QLD 4006, Australia.
  • Saggiomo SL; QIMR Berghofer Medical Research Institute, Brisbane, Herston, QLD 4006, Australia.
  • Nawaratna SSK; School of Medicine, University of Queensland, Brisbane, Herston, QLD 4006, Australia.
  • Poli M; Translational Venomics Laboratory, Madrid Institute for Advanced Studies in Food, Madrid 28049, Spain.
  • Reissmann R; Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072, Australia.
  • Gobert GN; QIMR Berghofer Medical Research Institute, Brisbane, Herston, QLD 4006, Australia.
  • Deutsch U; QIMR Berghofer Medical Research Institute, Brisbane, Herston, QLD 4006, Australia.
  • Engelhardt B; QIMR Berghofer Medical Research Institute, Brisbane, Herston, QLD 4006, Australia.
  • Brooks AJ; QIMR Berghofer Medical Research Institute, Brisbane, Herston, QLD 4006, Australia.
  • Jones A; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
  • Arosio P; Department for BioMedical Research (DBMR), University of Bern, Freiestrasse 1, CH-3012 Bern, Switzerland.
  • Ramm GA; QIMR Berghofer Medical Research Institute, Brisbane, Herston, QLD 4006, Australia.
Sci Signal ; 17(830): eade4335, 2024 Apr 02.
Article em En | MEDLINE | ID: mdl-38564492
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inflamassomos / Hepatopatias Limite: Animals Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inflamassomos / Hepatopatias Limite: Animals Idioma: En Ano de publicação: 2024 Tipo de documento: Article