Comparison of Different Betadine and Saline Combinations on Microorganisms: An Original Research.
J Pharm Bioallied Sci
; 16(Suppl 1): S219-S222, 2024 Feb.
Article
em En
| MEDLINE
| ID: mdl-38595466
ABSTRACT
Introduction:
Pathogenic bacteria in the oral cavity or a physiological microbiome imbalance can cause or maintain disease. Thus, this work examined a novel betadine-saline combination for antibacterial and antifungal activities. Materials andMethods:
This study was in vitro. Betadine, saline, and their mixtures were tested for Bacillus subtilis, Staphylococcus aureus (gram-positive), Pseudomonas aeruginosa, Escherichia coli, and Aspergillus niger (gram-negative). Pour plate and disc diffusion methods were used to test CFUs, DZI, and RZI for various agent combinations.Results:
For Lactobacillus acidophilus, Betadine 90% + saline 10% had the greatest DZI and RZI at 24 and 12 mm, respectively. For E. coli, Betadine 50% + saline 50% had the highest at 16 and 8 mm. Betadine 60% + saline 40% had 14 mm RZI and the highest antifungal activity.Conclusion:
The novel betadine-saline antibacterial and antifungal combination performed well. In vivo research should confirm the existing findings.
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article