Clinical characteristics of patients with refractory non-epileptic seizures.
Epilepsy Behav
; 155: 109783, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38642527
ABSTRACT
OBJECTIVES:
This incidence of non-epileptic seizures (NES) is estimated at 1-35 per 100,000 population. While many patients achieve remission, a significant fraction of patients have a poor prognosis despite optimal interventions. This study reports on the characteristics of patients with refractory NES diagnosed and treated at a comprehensive epilepsy centre.METHODS:
A retrospective review of admissions to the Epilepsy Monitoring Unit identified patients diagnosed with NES over a 6-year period. Patients with refractory NES were identified through review of medical files. A diagnosis of refractory NES was assigned when patients experienced ongoing NES at least 1 year after diagnostic video-EEG monitoring. Data pertaining to predisposing, precipitating and perpetuating factors was collected on all patients and a comparative analysis was conducted between refractory and non-refractory cases.RESULTS:
66 patients with NES were identified, 35% were deemed refractory. There was no significant difference amongst predisposing factors between the groups. Psychosocial adversity and a clear precipitant proximate to the onset of NES were significantly more common in the refractory cohort. Unemployment at time of diagnosis was a significant perpetuating factor associated with poor outcome.CONCLUSION:
This study provides insight into the features associated with refractory NES and may serve to improve prognostication and management in this disabling condition.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Convulsões
/
Eletroencefalografia
Limite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article