Precise prostate cancer diagnosis using fluorescent nanoprobes for detecting PSA and PSMA in serum.

Ouyang, Mingyi; Jia, Ming; Chang, Zixuan; Wang, Yinian; Wang, Keyi; Gao, Xiaonan; Tang, Bo

Ouyang, Mingyi; Jia, Ming; Chang, Zixuan; Wang, Yinian; Wang, Keyi; Gao, Xiaonan; Tang, Bo.

Afiliação

Ouyang M; College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of F
Jia M; Department of Cancer Center, The Secondary Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250033, P. R. China.
Chang Z; College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of F
Wang Y; College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of F
Wang K; College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of F
Gao X; College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of F
Tang B; College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of F

Chem Commun (Camb) ; 60(39): 5181-5184, 2024 May 09.

Article em En | MEDLINE | ID: mdl-38647078

ABSTRACT

ABSTRACT

Novel Au-Se bond-based nanoprobes were designed for concurrent detection of PSA and PSMA in serum samples, aiming to enhance the early diagnosis of prostate cancer. These probes demonstrate robust stability, specificity and accuracy, underscoring their potential as non-invasive tools for diagnosis.

Assuntos

Antígenos de Superfície; Corantes Fluorescentes; Glutamato Carboxipeptidase II; Ouro; Antígeno Prostático Específico; Neoplasias da Próstata; Humanos; Neoplasias da Próstata/sangue; Neoplasias da Próstata/diagnóstico; Masculino; Antígeno Prostático Específico/sangue; Glutamato Carboxipeptidase II/sangue; Corantes Fluorescentes/química; Antígenos de Superfície/sangue; Ouro/química

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Antígeno Prostático Específico / Glutamato Carboxipeptidase II / Corantes Fluorescentes / Ouro / Antígenos de Superfície Limite: Humans / Male Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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