Pro-Inflammatory Activation Suppresses TRAIL-induced Apoptosis of Acute Myeloid Leukemia Cells.

Kobyakova, Margarita I; Senotov, Anatoly S; Krasnov, Kirill S; Lomovskaya, Yana V; Odinokova, Irina V; Kolotova, Anastasia A; Ermakov, Artem M; Zvyagina, Alena I; Fadeeva, Irina S; Fetisova, Elena I; Akatov, Vladimir S; Fadeev, Roman S

Kobyakova, Margarita I; Senotov, Anatoly S; Krasnov, Kirill S; Lomovskaya, Yana V; Odinokova, Irina V; Kolotova, Anastasia A; Ermakov, Artem M; Zvyagina, Alena I; Fadeeva, Irina S; Fetisova, Elena I; Akatov, Vladimir S; Fadeev, Roman S.

Afiliação

Kobyakova MI; Institute of Theoretical and Experimental Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia. margaritaikobykova@mail.ru.
Senotov AS; Institute of Clinical and Experimental Lymphology, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, 630060, Russia.
Krasnov KS; Institute of Theoretical and Experimental Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia.
Lomovskaya YV; Institute of Theoretical and Experimental Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia.
Odinokova IV; Institute of Theoretical and Experimental Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia.
Kolotova AA; Institute of Theoretical and Experimental Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia.
Ermakov AM; Institute of Theoretical and Experimental Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia.
Zvyagina AI; Institute of Theoretical and Experimental Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia.
Fadeeva IS; Institute of Theoretical and Experimental Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia.
Fetisova EI; Institute of Theoretical and Experimental Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia.
Akatov VS; Institute of Theoretical and Experimental Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia.
Fadeev RS; Institute of Theoretical and Experimental Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290, Russia.

Biochemistry (Mosc) ; 89(3): 431-440, 2024 Mar.

Article em En | MEDLINE | ID: mdl-38648763

Assuntos

Apoptose; Leucemia Mieloide Aguda; Receptores do Ligante Indutor de Apoptose Relacionado a TNF; Ligante Indutor de Apoptose Relacionado a TNF; Humanos; Ligante Indutor de Apoptose Relacionado a TNF/metabolismo; Ligante Indutor de Apoptose Relacionado a TNF/farmacologia; Leucemia Mieloide Aguda/metabolismo; Leucemia Mieloide Aguda/patologia; Leucemia Mieloide Aguda/tratamento farmacológico; Apoptose/efeitos dos fármacos; Receptores do Ligante Indutor de Apoptose Relacionado a TNF/metabolismo; Receptores do Ligante Indutor de Apoptose Relacionado a TNF/genética; Células THP-1; Inflamação/metabolismo; Lipopolissacarídeos/farmacologia; Caspase 3/metabolismo

Palavras-chave

TRAIL-induced cell death; acute myeloid leukemia; pro-inflammatory cell activation; resistance

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Apoptose / Ligante Indutor de Apoptose Relacionado a TNF / Receptores do Ligante Indutor de Apoptose Relacionado a TNF Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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