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Arrhythmias and ion channelopathies causing sudden cardiac death in Hispanic/Latino and Indigenous populations.
Zaveri, Sahil; Chahine, Mohamed; Boutjdir, Mohamed.
Afiliação
  • Zaveri S; Cardiovascular Research Program, VA New York Harbor Healthcare System, New York, New York, USA.
  • Chahine M; Department of Medicine, SUNY Downstate Health Sciences University, New York, New York, USA.
  • Boutjdir M; CERVO Brain Research Center, Institut Universitaire en Santé Mentale de Québec, Québec City, Québec, Canada.
J Cardiovasc Electrophysiol ; 35(6): 1219-1228, 2024 Jun.
Article em En | MEDLINE | ID: mdl-38654386
ABSTRACT
The limited literature and increasing interest in studies on cardiac electrophysiology, explicitly focusing on cardiac ion channelopathies and sudden cardiac death in diverse populations, has prompted a comprehensive examination of existing research. Our review specifically targets Hispanic/Latino and Indigenous populations, which are often underrepresented in healthcare studies. This review encompasses investigations into genetic variants, epidemiology, etiologies, and clinical risk factors associated with arrhythmias in these demographic groups. The review explores the Hispanic paradox, a phenomenon linking healthcare outcomes to socioeconomic factors within Hispanic communities in the United States. Furthermore, it discusses studies exemplifying this observation in the context of arrhythmias and ion channelopathies in Hispanic populations. Current research also sheds light on disparities in overall healthcare quality in Indigenous populations. The available yet limited literature underscores the pressing need for more extensive and comprehensive research on cardiac ion channelopathies in Hispanic/Latino and Indigenous populations. Specifically, additional studies are essential to fully characterize pathogenic genetic variants, identify population-specific risk factors, and address health disparities to enhance the detection, prevention, and management of arrhythmias and sudden cardiac death in these demographic groups.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Hispânico ou Latino / Morte Súbita Cardíaca / Predisposição Genética para Doença / Canalopatias Limite: Adult / Female / Humans / Male / Middle aged País como assunto: America do norte Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Hispânico ou Latino / Morte Súbita Cardíaca / Predisposição Genética para Doença / Canalopatias Limite: Adult / Female / Humans / Male / Middle aged País como assunto: America do norte Idioma: En Ano de publicação: 2024 Tipo de documento: Article