Copper-Catalyzed Chemoselective Coupling of N-Dithiophthalimides and Alkyl Halides: Synthesis of Unsymmetrical Disulfides and Sulfides.
Org Lett
; 26(17): 3634-3639, 2024 May 03.
Article
em En
| MEDLINE
| ID: mdl-38660998
ABSTRACT
In this paper, we report an unprecedented copper-catalyzed disulfides or sulfides coupling reaction involving unactivated alkyl halides and N-dithiophthalimides. This reaction can be conducted under mild conditions using low-cost metal catalysts and exhibits high chemical selectivity and functional group compatibility, enabling the efficient assembly of various sulfides and disulfides.
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MEDLINE
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En
Ano de publicação:
2024
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Article