Hydrophilic Coating Microstructure Mediates Acute Drug Transfer in Drug-Coated Balloon Therapy.

Shazly, Tarek; Eberth, John F; Kostelnik, Colton J; Uline, Mark J; Chitalia, Vipul C; Spinale, Francis G; Alshareef, Ahmed; Kolachalama, Vijaya B

Shazly, Tarek; Eberth, John F; Kostelnik, Colton J; Uline, Mark J; Chitalia, Vipul C; Spinale, Francis G; Alshareef, Ahmed; Kolachalama, Vijaya B.

Afiliação

Shazly T; Department of Biomedical Engineering Program, College of Engineering and Computing, University of South Carolina, Columbia, South Carolina 29208, United States.
Eberth JF; Department of Mechanical Engineering, College of Engineering and Computing, University of South Carolina, Columbia, South Carolina 29208, United States.
Kostelnik CJ; Cardiovascular Translational Research Center, University of South Carolina, Columbia, South Carolina 29208, United States.
Uline MJ; Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania 19104, United States.
Chitalia VC; Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania 19104, United States.
Spinale FG; Aerospace Engineering and Engineering Mechanics, The University of Texas at Austin, Austin, Texas 78712, United States.
Alshareef A; Department of Biomedical Engineering Program, College of Engineering and Computing, University of South Carolina, Columbia, South Carolina 29208, United States.
Kolachalama VB; Cardiovascular Translational Research Center, University of South Carolina, Columbia, South Carolina 29208, United States.

ACS Appl Bio Mater ; 7(5): 3041-3049, 2024 05 20.

Article em En | MEDLINE | ID: mdl-38661721

Assuntos

Materiais Revestidos Biocompatíveis; Interações Hidrofóbicas e Hidrofílicas; Paclitaxel; Paclitaxel/química; Paclitaxel/farmacologia; Paclitaxel/administração & dosagem; Materiais Revestidos Biocompatíveis/química; Teste de Materiais; Polietilenoglicóis/química; Tamanho da Partícula; Humanos; Ureia/química; Angioplastia com Balão; Sistemas de Liberação de Medicamentos; Propriedades de Superfície

Palavras-chave

coating microstructure; drug-coated balloon; excipient; paclitaxel; polyethylene glycol; urea

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Paclitaxel / Materiais Revestidos Biocompatíveis / Interações Hidrofóbicas e Hidrofílicas Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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