Preparation, biological activity and antibacterial properties of tantalum surface-doped Ca2+/Zn2+nanorods.
Nanotechnology
; 35(30)2024 May 10.
Article
em En
| MEDLINE
| ID: mdl-38663375
ABSTRACT
In this research, we utilize porous tantalum, known for its outstanding elastic modulus and biological properties, as a base material in biomedical applications. The human skeletal system is rich in elements like Ca and Zn. The role of Zn is crucial for achieving a spectrum of sterilizing effects, while Ca is known to effectively enhance cell differentiation and boost cellular activity. The focus of this study is the modification of porous tantalum using a hydrothermal method to synthesize Ca2+/Zn2+-doped Ta2O5nanorods. These nanorods are subjected to extensive characterization techniques to confirm their structure and composition. Additionally, their biological performance is evaluated through a range of tests, including antibacterial assessments, MTT assays, and bacteria/cell scanning electron microscopy (SEM) analyses. The objective is to determine the most effective method of surface modification for porous tantalum, thereby laying a foundational theoretical framework for its surface enhancement.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tantálio
/
Zinco
/
Cálcio
/
Antibacterianos
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article