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Advancing genomics to improve health equity.
Madden, Ebony B; Hindorff, Lucia A; Bonham, Vence L; Akintobi, Tabia Henry; Burchard, Esteban G; Baker, Kellan E; Begay, Rene L; Carpten, John D; Cox, Nancy J; Di Francesco, Valentina; Dillard, Denise A; Fletcher, Faith E; Fullerton, Stephanie M; Garrison, Nanibaa' A; Hammack-Aviran, Catherine M; Hiratsuka, Vanessa Y; Hildreth, James E K; Horowitz, Carol R; Hughes Halbert, Chanita A; Inouye, Michael; Jackson, Amber; Landry, Latrice G; Kittles, Rick A; Leek, Jeff T; Limdi, Nita A; Lockhart, Nicole C; Ofili, Elizabeth O; Pérez-Stable, Eliseo J; Sabatello, Maya; Saulsberry, Loren; Schools, Lorjetta E; Troyer, Jennifer L; Wilfond, Benjamin S; Wojcik, Genevieve L; Cho, Judy H; Lee, Sandra S-J; Green, Eric D.
Afiliação
  • Madden EB; Office of the Director, National Human Genome Research Institute, Bethesda, MD, USA. ebony.madden@nih.gov.
  • Hindorff LA; Office of the Director, National Human Genome Research Institute, Bethesda, MD, USA.
  • Bonham VL; Office of the Director, National Human Genome Research Institute, Bethesda, MD, USA.
  • Akintobi TH; Department of Community Health and Preventative Medicine, Morehouse School of Medicine, Atlanta, GA, USA.
  • Burchard EG; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, CA, USA.
  • Baker KE; Whitman-Walker Institute, Washington, DC, USA.
  • Begay RL; Centers for American Indian and Alaska Native Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • Carpten JD; Comprehensive Cancer Center, City of Hope, Duarte, CA, USA.
  • Cox NJ; Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA.
  • Di Francesco V; Office of the Director, National Human Genome Research Institute, Bethesda, MD, USA.
  • Dillard DA; Department of Medical Education and Clinical Sciences, Washington State University College of Medicine, Seattle, WA, USA.
  • Fletcher FE; Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, TX, USA.
  • Fullerton SM; Department of Bioethics and Humanities, University of Washington, Seattle, WA, USA.
  • Garrison NA; Institute for Society and Genetics, University of California, Los Angeles, Los Angeles, CA, USA.
  • Hammack-Aviran CM; Institute for Precision Health, UCLA David Geffen School of Medicine, Los Angeles, CA, USA.
  • Hiratsuka VY; Division of General Internal Medicine and Health Services Research, UCLA David Geffen School of Medicine, Los Angeles, CA, USA.
  • Hildreth JEK; Department of Health Policy, Vanderbilt University, Nashville, TN, USA.
  • Horowitz CR; Center for Human Development, University of Alaska Anchorage, Anchorage, AK, USA.
  • Hughes Halbert CA; Meharry Medical College, Nashville, TN, USA.
  • Inouye M; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Jackson A; Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA.
  • Landry LG; Department of Public Health and Primary Care, University of Cambridge Victor Phillip Dahdaleh Heart and Lung Research Institute, Cambridge, UK.
  • Kittles RA; Office of the Director, National Human Genome Research Institute, Bethesda, MD, USA.
  • Leek JT; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Limdi NA; Morehouse School of Medicine, Atlanta, GA, USA.
  • Lockhart NC; Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA, USA.
  • Ofili EO; Department of Neurology, University of Alabama, Birmingham School of Medicine, Birmingham, AL, USA.
  • Pérez-Stable EJ; Office of the Director, National Human Genome Research Institute, Bethesda, MD, USA.
  • Sabatello M; Department of Medicine, Morehouse School of Medicine, Atlanta, GA, USA.
  • Saulsberry L; National Institute on Minority Health and Health Disparities, Bethesda, MD, USA.
  • Schools LE; Center for Precision Medicine and Genomics, Columbia University, New York, NY, USA.
  • Troyer JL; Department of Medical Humanities and Ethics, Columbia University, New York, NY, USA.
  • Wilfond BS; Department of Public Health Sciences, The University of Chicago, Chicago, IL, USA.
  • Wojcik GL; Common Fund, National Institutes of Health, Bethesda, MD, USA.
  • Cho JH; Office of the Director, National Human Genome Research Institute, Bethesda, MD, USA.
  • Lee SS; Department of Pediatrics, University of Washington, Seattle, WA, USA.
  • Green ED; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Nat Genet ; 56(5): 752-757, 2024 May.
Article em En | MEDLINE | ID: mdl-38684898
ABSTRACT
Health equity is the state in which everyone has fair and just opportunities to attain their highest level of health. The field of human genomics has fallen short in increasing health equity, largely because the diversity of the human population has been inadequately reflected among participants of genomics research. This lack of diversity leads to disparities that can have scientific and clinical consequences. Achieving health equity related to genomics will require greater effort in addressing inequities within the field. As part of the commitment of the National Human Genome Research Institute (NHGRI) to advancing health equity, it convened experts in genomics and health equity research to make recommendations and performed a review of current literature to identify the landscape of gaps and opportunities at the interface between human genomics and health equity research. This Perspective describes these findings and examines health equity within the context of human genomics and genomic medicine.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Equidade em Saúde / Genômica Limite: Humans País como assunto: America do norte Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Equidade em Saúde / Genômica Limite: Humans País como assunto: America do norte Idioma: En Ano de publicação: 2024 Tipo de documento: Article