Prognostic models of drug-induced neutralizing antibody formation in patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis treated with TNF-&#945; blockersockers.

Kraev, Krasimir; Hristov, Bozhidar; Uchikov, Petar; Kraeva, Mariya; Geneva-Popova, Mariela; Popova, Stanislava; Basheva-Kraeva, Yordanka; Stoyanova, Nina S; Mitkova-Hristova, Vesela

Prognostic models of drug-induced neutralizing antibody formation in patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis treated with TNF-α blockersockers.

Kraev, Krasimir; Hristov, Bozhidar; Uchikov, Petar; Kraeva, Mariya; Geneva-Popova, Mariela; Popova, Stanislava; Basheva-Kraeva, Yordanka; Stoyanova, Nina S; Mitkova-Hristova, Vesela.

Afiliação

Kraev K; Medical University of Plovdiv, Plovdiv, Bulgaria.
Hristov B; Medical University of Plovdiv, Plovdiv, Bulgaria.
Uchikov P; Medical University of Plovdiv, Plovdiv, Bulgaria.
Kraeva M; Medical University of Plovdiv, Plovdiv, Bulgaria.
Geneva-Popova M; Medical University of Plovdiv, Plovdiv, Bulgaria.
Popova S; Medical University of Plovdiv, Plovdiv, Bulgaria.
Basheva-Kraeva Y; Medical University of Plovdiv, Plovdiv, Bulgaria.
Stoyanova NS; Medical University of Plovdiv, Plovdiv, Bulgaria.
Mitkova-Hristova V; Medical University of Plovdiv, Plovdiv, Bulgaria.

Folia Med (Plovdiv) ; 66(2): 188-195, 2024 Apr 30.

Article em En | MEDLINE | ID: mdl-38690813

ABSTRACT

ABSTRACT

AIM:

This study aimed to construct prognostic mathematical models utilizing multifactorial regression analysis to assess the risk of developing drug-induced neutralizing antibodies in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis treated with tumor necrosis factor alpha blockers.

Assuntos

Anticorpos Neutralizantes; Artrite Psoriásica; Artrite Reumatoide; Espondilite Anquilosante; Fator de Necrose Tumoral alfa; Humanos; Espondilite Anquilosante/tratamento farmacológico; Espondilite Anquilosante/imunologia; Artrite Reumatoide/tratamento farmacológico; Artrite Reumatoide/imunologia; Artrite Psoriásica/tratamento farmacológico; Artrite Psoriásica/imunologia; Fator de Necrose Tumoral alfa/antagonistas & inibidores; Fator de Necrose Tumoral alfa/imunologia; Prognóstico; Masculino; Feminino; Pessoa de Meia-Idade; Adulto; Antirreumáticos/uso terapêutico; Modelos Teóricos

Palavras-chave

anti-drug antibodies prognostic model

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Espondilite Anquilosante / Artrite Psoriásica / Fator de Necrose Tumoral alfa / Anticorpos Neutralizantes Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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