[Treatment strategies for recurrent rectal cancer]. / Therapiestrategien beim Rektumkarzinomrezidiv.
Chirurgie (Heidelb)
; 95(6): 495-509, 2024 Jun.
Article
em De
| MEDLINE
| ID: mdl-38739162
ABSTRACT
Multimodal treatment approaches with neoadjuvant radiotherapy and chemotherapy followed by oncological and total mesorectal excision (TME) have significantly reduced the recurrence rate even in locally advanced rectal cancer. Nevertheless, up to 10% of patients develop a local relapse. Surgical R0 resection is the only chance of a cure in the treatment of locally recurrent rectal cancer (LRRC). Due to the altered anatomy and physiology of the true pelvis as a result of the pretreatment and operations as well as the localization and extent of the recurrence, the treatment decision is individualized and remains a challenge for the interdisciplinary team. Even locally advanced tumors with involvement of adjacent structures can be treated in designated centers using multimodal treatment concepts with potentially curative intent.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Retais
/
Recidiva Local de Neoplasia
Limite:
Humans
Idioma:
De
Ano de publicação:
2024
Tipo de documento:
Article